FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention discloses a sublingual tablet pharmaceutical composition for treating cerebrovascular diseases. Pharmaceutical composition is characterized by that it contains edaravone, (+)–2-borneol, excipient, filler, binder, disintegrator and lubricant. Excipient includes mannitol and copovidone.
EFFECT: pharmaceutical composition provides improved stability and release rate of edaravone and (+)–2-borneol, high bioavailability and cerebral permeability with convenient sublingual method of administration.
7 cl, 20 ex, 3 tbl, 3 dwg
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