NA MIKHAILOVA'S METHOD FOR AUGMENTATION OF LABOUR Russian patent published in 2010 - IPC A61K38/11 A61P15/04 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to obstetrics and clinical pharmacology, and can be used for augmentation of uterine contractions with oxytocin solution in full-term pregnancy. An oxytocin dose is pre-calculated from the relation D_DR. ⁼ 1IU M·/80, where D_DR. is a required dose of oxytocin in IU, M is a digital expression of weight of a parturient woman, kg. Oxytocin is dissolved in 300-500 ml of 0.9% sodium chloride. In the absence of labour activity, the preparation is introduced continuously, starting with 1 drop a minute and once-a-minute increasing introduction rate 1 to more drops to the first uterine contractions. The effective introduction rate is calculated, and the preparation is introduced during periods of uterine relaxation. The insufficient labour activity requires a single dose increased in 1.5 times. In overdosing, introduction of oxytocin solution is stopped with immediately venous infusion of 0.9% sodium chloride.

EFFECT: method provides accurate dosage of oxytocin solution and reduced by-effects of augmentation.

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