METHOD FOR INHIBITION OF HEPATOCYTE PROLIFERATION, METHOD FOR INHIBITION OF HEPATOCYTE CELL ADHESION AND METHOD FOR INHIBITION OF BIOLOGICAL ACTIVITY ANGPTL4 IN HEPATOCYTES OR HEPATOCYTE PRECURSORS Russian patent published in 2010 - IPC C12N5/00 C12N15/00 C07K14/515 C07K16/00 

Abstract RU 2380411 C2

FIELD: medicine.

SUBSTANCE: as an ANGPTL4 antagonist, anti-ANGPTL4-antibody is used. The invention allows for making the ANGPTL4 antagonist able to inhibit hepatocyte proliferation and cell adhesion, and inhibiting ANGPTL4 in hepatocytes or hepatocyte precursors.

EFFECT: improved properties of the compound.

4 cl, 20 dwg, 9 ex

Similar patents RU2380411C2

Title Year Author Number
ANGIOPOIETIC ANGIOPOIETIN-LIKE PROTEIN 4 INHIBITORS, IN COMBINATIONS AND APPLICATION 2005
  • Ferrara Napoleone
  • Gerber Khans-Peter
  • Ljan Sjao Khuan
RU2392966C2
MODULATORS OF HEPATOCYTE GROWTH FACTOR ACTIVATOR 2005
  • Kirkkhofer Dehniel K.
  • Vu Jan
RU2418004C2
METHODS AND COMPOSITIONS FOR ACTIVATION MODULATION OF HEPATOCYTE GROWTH FACTOR 2005
  • Kirkhkhofer Dehniel K.
  • Moran Pol M.
  • Pik Mark D.
RU2405041C2
NEW COMPOSITION AND METHODS FOR THERAPY OF IMMNUNE-ASSOCIATED DISEASES WITH IMMUNITY 2004
  • Klark Khilari
  • Iton Dehniel L.
  • Vranik Bernd
  • Oujan Vehn'Tszjun'
  • Gonzales Lino
  • Lojet Kelli M.
RU2375078C2
METHODS OF INHIBITING OCULAR ANGIOGENESIS 2009
  • Junge Kharal'D J.
  • E. Vehjlan'
RU2530583C2
INHIBITION OF TUMOUR METASTASES BY ANTIBODIES AGAINST NEUROPILINE-2 2007
  • U Jan'
  • Ljan Vehj-Chin
  • Uotts Rajan Dzhefferson
  • Bagri Anil Durgadas
RU2437677C2
METHOD OF INHIBITING ANGIOGENESIS BY EGFL8 ANTAGONISTS 2009
  • E Vehjlan'
  • Lu Khan'
RU2486200C2
ANGIOGENESIS INHIBITION 2008
  • Ferrara Napoleon
  • Shodzhejn Farbod
  • U Sjumin'
  • Chzhun Tsujlin
RU2471498C2
ANTI-CCR2 ANTIBODIES 2009
  • Beluski, Shelli Sims
  • Grin, Larri L.
  • Liang, Mejna
  • Glehjd'Ju, Ronald P.
  • Keller, Brehdli T.
  • Ogava, Sindzi
  • Radzhpal, Arvind
  • Tilaska, Lori A.
RU2547595C2
TECHNIQUES AND COMPOSITIONS USED TO INHIBIT αβ-CAUSED ANGIOGENESIS 1997
  • Bruks Piter
  • Cheresh Dehvid A.
  • Fridlehnder Martin
  • Silletti Stiven
RU2195312C2

RU 2 380 411 C2

Authors

Banting Stjuart

Gerber Khans-Peter

Ljan Sjao Khuan

Dates

2010-01-27Published

2005-07-19Filed