11b-(HET)ARYL-2,3,611b-TETRAHYDROOXAZOLO[2',3':2,1]PYRROLO[3,4-b]QUINOLIN-5,11-DIONES AND SYNTHESIS METHOD THEREOF Russian patent published in 2010 - IPC C07D498/12 A61K31/4738 

FIELD: chemistry.

SUBSTANCE: invention relates to 11b-(het)aryl-2,3,6,11b-tetrahydrooxazolo[2'_,3':2,1]pyrrolo [3,4-b]quinolin-5,11-diones with general formula 1 R¹=Ar, Het; R²=H, Alk, OAlk, halogen; R³ - H, Alk, OAlk, halogen; R⁴=H, Alk, OAlk, halogen and to a synthesis method which involves reacting initial 3-(het)aroyl-4-oxo-1,4-dihydro-2-quinolincarboxylate with monoethanolamine in ratio 1:1 in methanol, ethanol, tetrahydrofuran, toluene, dioxane while heating in the presence or absence of acetic acid for 2-24 hours (control using thin-layer chromatography).

EFFECT: formula 1 compounds have potential for use as low-toxicity substances with biological activity, for example antimicrobial, antiviral and anticonvulsant; method of producing formula 1 compounds is easy to implement, safe, does not require special conditions, allows for obtaining substances which can not be produced using other methods.

2 cl, 10 ex