ANALGESIC MEANS Russian patent published in 2017 - IPC A61K31/47 A61K31/4709 A61K31/381 A61P29/00 C07D215/22 C07D215/233 C07D409/12 

FIELD: pharmacology.

SUBSTANCE: invention relates to an analgesic means in which individual substituted quinoline-4(1H)-ones of general formula 1 their salts or compositions based on them are active substances, and which can be used as an anesthetic to treat humans and animals, where R¹ = phenyl unsubstituted or substituted by one substituent selected from alkyl (C1-C4), alkoxy (OC1-OC4), halogen; phenyl substituted by two substituents selected from methyl, ethyl, methoxy, ethoxy or halogen; unsubstituted naphthyl, unsubstituted thienyl or thienyl substituted by one substituent selected from methyl or halogen; unsubstituted furyl, C4-alkyl, OMe; R²+R³ = =O, =NOMe, R⁴=H, COOMe, COOH; R⁵= H, Me; R^6th= H, Me, OMe, Et, halogen; R^7th= H, halogen, CN; R⁸= H, alkyl (C1-C4), halogen, CN.

EFFECT: expansion arsenal of anesthetic means.

2 tbl, 7 ex