NOVEL CRYSTALLINE FORM OF (3-CYANO-1N-INDOL-7-YL)-[4-(4-FLUOROPHENETHYL)PIPERAZIN-1-YL]METHANONE HYDROCHLORIDE Russian patent published in 2010 - IPC C07D209/42 A61K31/496 A61P25/18 A61P25/20

Abstract RU 2383532 C2

FIELD: chemistry.

SUBSTANCE: invention relates to crystalline form of B (3-cyano-1N-indol-7-yl)-[4-(4-fluorophenethyl)piperazin-1-yl] methanone hydrochloride, as well as to synthesis method thereof by passing HCl gas through a solution of (3-cyano-1N-indol-7-yl)-[4-(4-fluorophenethyl)piperazin-1-yl] methanone, separating the formed residue from the reaction mixture and drying.

EFFECT: end product can be used in medicine as a medicinal agent which has antagonistic effect on 5-HT_2A receptor.

4 cl, 4 dwg, 4 tbl, 4 ex

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RU 2 383 532 C2

Authors

Bate Andreas

Khel'Fert Bernd

Knirime Ral'F

Zal Kristof

Kajner Ronal'D

Dates

2010-03-10—Published

2005-09-08—Filed