CHEWING-RESISTANT CAPSULE Russian patent published in 2010 - IPC A61K9/48 A61K31/20 A61P25/16 

Abstract RU 2384325 C2

FIELD: medicine.

SUBSTANCE: invention refers to a soft capsule containing a compound, causing irritation in oral cavity, particularly, (2R)-2-propyloctane acid or its salt. Said compounds are suitable as an agent to prevent, treat and/or delay of progression of symptoms of various neurodegenerative diseases. The capsule exhibits durability 150 to 400 H when crack-tested, decay time 3 to 10 minutes when disintegration tested.

EFFECT: soft capsule under the invention is chewing-resistant, it can be ingested safely without sensation of burning, hotness, pain in oral cavity; the capsule ensures long storage without solubility delay.

34 cl, 24 tbl, 8 ex

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RU 2 384 325 C2

Authors

Okamoto Itiro

Mijamoto Judzi

Nisimura Khidekatsu

Dates

2010-03-20Published

2005-06-10Filed