FIELD: medicine, pharmaceutics.
SUBSTANCE: aqueous pharmaceutical composition containing: a) 0.005-10 wt % of one or more water-soluble pharmaceutically active components or their pharmaceutically acceptable salts; b) 0.01 to 10 wt % of hydroxypropylmethylcellulose with viscosity 2500 to 5500 sP (mPa*s); and c) a buffer for maintaining a pH level of a pharmaceutical composition within 5 to 7, can be prepared by a method which involves: i) dissolution of said components in water to form an aqueous solution, and ii) filtering of the aqueous solution prepared at the stage i), through a filter of pore size ≥ 1 micron and ≤10 micron.
EFFECT: compositions prepared by said method are able to exhibit improved mucoadhesive ability and stability.
13 cl, 2 tbl, 8 ex
