FIELD: medicine, pharmacy.
SUBSTANCE: invention relates to a pharmaceutical composition for controlled release that comprises a medicinal agent, polyethylene oxide with molecular mass 2000000 Da or above and a special size-regulating agent for indicated polyethylene oxide and wherein indicated medicinal agent and size-regulating agent are dispersed uniformly in polyethylene oxide. Also, invention relates to a method for preparing indicated pharmaceutical composition for controlled release and a pharmaceutical preparation for controlled release comprising indicated pharmaceutical composition for controlled release. The pharmaceutical composition with controlled release possesses good uniformity of the content and can be prepared using polyethylene oxide powder particles showing properties suitable for making tablets that is prepared by uniform dispersing a size-regulating agent for polyethylene oxide.
EFFECT: improved and valuable pharmaceutical properties of composition.
32 cl, 1 tbl, 16 ex
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Authors
Dates
2007-01-20—Published
2003-12-24—Filed