VACCINE ASSOCIATED AGAINST PSEUDOMONOSE AND ENTEROCOCCAL INFECTION IN NUTRIAS Russian patent published in 2010 - IPC A61K39/116 A61P31/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention concerns veterinary medicine. A vaccine contains cell suspensions of pure cultures of activators of pseudomonose Pseudomonas aeruginosa and enterococcal infection Enterococcus faecalis prepared by sampling involved organs from dead nutrias of a local epizootic centre, preparation of a suspension, inoculation for differential diagnostic mediums, recovery of pure cultures of activators and their separate cultivation in a plain broth with glucose to concentration of microbial cells 4-5 billion per 1 cm³. The vaccine also contains formalin and aluminium hydroxide in the following ratio, wt %: cell suspensions of pure cultures of the activator of pseudomonose Pseudomonas aeruginosa recovered from involved organs from dead nutrias from the local epizootic centre, in a nutrient medium with titre 4-5 billion of microbial cells per 1 cm³ - 38.0-41.5, cell suspensions of pure cultures of the activator of enterococcal infection Enterococcus faecalis recovered from involved organs from dead nutrias from the local epizootic centre in the nutrient medium with titre of 4-5 billion of microbial cells per 1 cm³ - 38.0-41.5, glucose - 2.0-1.0, formalin - 2.0-1.5, aluminium hydroxide - the rest.

EFFECT: prepared vaccine is safe, specific and immunogenic.

1 tbl, 5 ex