VACCINE, ASSOCIATED AGAINST NUTRIA SALMONELLOSIS AND ENTEROCOCCUS INFECTION Russian patent published in 2007 - IPC A61K39/09 A61K39/112 A61P31/04 

FIELD: veterinary, vaccines.

SUBSTANCE: claimed vaccine contains as antigens pure culture cell suspension of causal organisms of salmonellosus Salmonella typhimurium and enterococcus infection Streptococcus fecalis, obtained by sampling of damaged organs of fallen nutrias from local epizootic focus, suspension preparation, seeding on differential diagnostic media, isolation of causal organism pure cultures. Culturing is carried out separately in meat-and-peptone broth with glucose at microbial cell concentration of 4-5 bln per 1 cm³, cells are mixed in ratio of 1:2, formalin and aluminum hydroxide are introduced in the next component ratio (mass %): pure culture cell suspension of causal organisms of salmonellosus Salmonella typhimurium isolated from local epizootic focus in broth with titer of 4-5 bln per 1 cm³ 22.5-27.5; pure culture cell suspension of causal organisms of enterococcus infection Streptococcus fecalis isolated from local epizootic focus in broth with titer of 4-5 bln per 1 cm³ 50.5-55.0-27.5; glucose 2.0-1.0; formalin 2.0-1.5; and balance: aluminum hydroxide.

EFFECT: associated vaccine with increased specificity and effectiveness without negative side effects.

1 tbl, 5 ex