METHOD OF NORMALISING FUNCTIONAL REACTIVITY OF CARDIOVASCULAR SYSTEM IN ARTERIAL HYPERTENSION, DYSLIPIDEMIA, IMPAIRED GLUCOSE TOLERANCE AND ABDOMINAL OBESITY Russian patent published in 2010 - IPC A61K31/41 A61K31/426 A61P5/50 A61H1/00 A23L1/29 

Abstract RU 2390337 C1

FIELD: medicine.

SUBSTANCE: invention concerns normalising functional reactivity of cardiovascular system (CVS) in arterial hypertension, dyslipidemia, impaired glucose tolerance and abdominal obesity. That is ensured by estimating the condition of functional reactivity of the CVS in psychoemotional load, with recording systolic, diastolic, average dynamic pressure (PBav.dyn.) and heart rate (HR). These data are used to evaluate a functional responsiveness index (FRI) before and after stress by formula: FRI=(BPav.dyn. x HR)/100 (standard units). The post-load value PFR increased more than by 20 standard units requires the complex therapy including individually prescribed hypocaloric diet calculated by formula considering sex and age, rationally graduated static and dynamic physical activity, and introduction of losartan in a dose of 50 mg once in the morning, and pioglitazone in a dose of 30 mg once in the morning at least within 4 months.

EFFECT: such complex drug-induced and drug-free therapy combined with empirically prescribed treatment length provides normalisation of functional reactance of the CVS in the given group of the patients due to potentiation of therapeutic effect of separate components of an individual care.

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Authors

Medvedev Il'Ja Nikolaevich

Kumova Tat'Jana Aleksandrovna

Danilenko Oleg Anatol'Evich

Bespartochnyj Boris Dmitrievich

Zavalishina Svetlana Jur'Evna

Krasnova Evgenija Gennad'Evna

Dates

2010-05-27Published

2009-04-01Filed