Show metadata Hide metadata

(19)

(11)

2 391 101

(13)

(51)

IPC

A61K31/4995(2006-01-01)

A61K31/282(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2005141408/15, 2004-06-01

(24)

Start date

2004-06-01

(22)

Actual filing date

2004-06-01

(45)

Published

2010-06-10

(72)

Inventor

D'Inkal'Chi MauritsioDzhanni LukaDzhavatstsi RafaehllaGarsija Martin MargaritaDzhadson JanKhimeno Don'Jake Khose MarijaSessa Krist'Jana

(73)

Holder

Farma Mar, S.A.U.

COMBINED APPLICATION OF ECTEINASCIDIN-743 AND PLATINUM-CONTAINING ANTI-TUMOUR COMPOUNDS Russian patent published in 2010 - IPC A61K31/4995 A61K31/282 A61P35/00

Abstract RU 2391101 C2

FIELD: medicine.

SUBSTANCE: invention relates to method of treating human patient with cancer by means of combined therapy with application of ET-743 in doses smaller than 1200 mcg/ m² per day and platinum anti-tumour agent - carboplatin in doses from 200 to 400 mcg/ m² per day. Application of ET-743 in combination with carboplatin in the same range of dosage as it is used in case of individual carboplatin introduction results in overcoming of resistance to platinum anti-tumour compound without increase of toxicity of each medication.

EFFECT: invention also relates to medical set which includes combination of ET-743 and carboplatin in said dosages, pharmaceutically acceptable carrier and treatment scheme instruction.

29 cl, 10 tbl, 5 ex

Similar patents RU2391101C2

Title	Year	Author	Number
COMPOSITION AND UTILIZATION OF ET743 FOR MALIGNANT TUMOR TREATMENT	2000	Kvitkovich Ehsteban Demetri Dzhordzh Dehniel Gusman Sesilija Khimeno Khose Lopes Lasaro Luis Misse Zhan Lui Tvelvz K. Fon Khoff Dehniel D.	RU2266734C2
COMBINED CHEMOTHERAPY	2001	Smit Mark Pirt Stefens Trevor Charl'Z	RU2284818C2
COMBINED CHEMOTHERAPY	2006	Smit Mark Pirt Stefens Trevor Charl'Z	RU2429838C2
COMBINED CHEMOTHERAPY	2010	Smit Mark Pirt Stefens Trevor Charlz	RU2587013C2
PEGYLATED LIPOSOMAL DOXORUBICINUM IN COMBINATION WITH ECTEINESCIDIN 743	2005	Zhill' Ehrar Sternas Lars-Aksel' Trifan Ovid Van De Vel'De Khel'Gi Tajtel'Baum Ehjpril	RU2359700C2
IMPROVED SCHEME OF USING ANTITUMOR COMPOUND IN CANCER THERAPY	2002	Khimeno Khose Ruis Kasado Ana Lopes Lasaro Luis Rovinski Ehrik Idal'Go Manuehl'	RU2306933C2
TREATMENT OF MALIGNANT TUMOR WITH APLIDINE	2000	Fehjrklot Glinn Tomas Tvelvz Kris Pas-Ares Luis	RU2261104C2
METHOD FOR ENHANCING EFFECTIVENESS OF ANTITUMOR AGENTS	2000	Pajver M. Stiven Silver Dehvid F.	RU2271829C2
COMBINATION THERAPY WITH AN ANTITUMOR ALKALOID	2011	Moneo Okanja Viktorija Santamarija Nunes Khema Garsia Fernandes Luis Fransisko Galmarini Karlos Marija Gilen Navarro Marija Khose Aviles Marin Pablo Manuel	RU2605335C2
COMBINATION THERAPY WITH ANTITUMOR ALKALOID	2018	Moneo Ocana, Victoria Santamaria Nunez, Gema Garcia Fernandez, Luis Francisco Galmarini, Carlos Maria Guillen Navarro, Maria Jose Aviles Marin, Pablo Manuel	RU2757373C2

RU 2 391 101 C2

Authors

D'Inkal'Chi Mauritsio

Dzhanni Luka

Dzhavatstsi Rafaehlla

Garsija Martin Margarita

Dzhadson Jan

Khimeno Don'Jake Khose Marija

Sessa Krist'Jana

Dates

2010-06-10—Published

2004-06-01—Filed