COMBINED CHEMOTHERAPY Russian patent published in 2006 - IPC A61K31/337 A61K31/4425 A61K9/00 A61P35/00 

FIELD: pharmaceutics.

SUBSTANCE: the suggested composition includes platinum-based compound with spatially complicated coordination and not platinum-based anti-cancer agent, and pharmaceutically acceptable carrier or solvent; the innovation deals with their application for obtaining medicinal preparation for inhibiting the growth of tumor cells in such a patient; with the method to inhibit the growth of tumor cells due to introducing for a patient efficient quantity of the mentioned therapeutic combined product or pharmaceutical composition that inhibits the growth of tumor cells according to the present innovation; in particular, when platinum-based compound with spatially complicated coordination is being (SP-4-3)-(cis-amine dichlorine-[2-methylpyridine]platinum (II) or its promedicine one should choose not platinum-based anti-cancer agent out of taxol, haemcytabin, navelbin, doxyl, 5-FU and taxoter. The present innovation enables to overcome resistance to cisplatin and prevent platinum-associated toxicity.

EFFECT: higher efficiency.

18 cl