MANUFACTURE METHOD OF CALCIUM PHOSPHATE-BASED POROUS MATERIAL Russian patent published in 2010 - IPC A61L27/12 A61K35/32 A61F2/28 A61P19/00 

Abstract RU 2392007 C2

FIELD: medicine.

SUBSTANCE: invention belongs to medicine and biotechnology, notably to manufacture methods of bone implant materials. Method includes dry mix preparation, moulding and burning. Dry mix includes calcium phosphate powder and pore-formative addition. Synthesised by coprecipitation from soluble salts of calcium and soluble phosphates, calcium phosphate must have mole ratio Ca/P between 1.0-1.5; as pore-formative addition is used alkali metal acetate, mixed within dry mix preparation with alkali metal hydroxide in ratio acetate/ hydroxide between 75/25-95-5; 6-10 wt % of alkali metal acetate and hydroxide mix is added to calcium phosphate, burning is performed at 1050-1150 °C.

EFFECT: invention provides calcium phosphate-based porous material manufacture without glass-powder addition, demanding previous labour-intensive preparation and forming in material amorphous phase resistant to biodegradation.

2 cl, 3 ex, 1 tbl

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Authors

Safronova Tat'Jana Viktorovna

Kornejchuk Svetlana Aleksandrovna

Putljaev Valerij Ivanovich

Tret'Jakov Jurij Dmitrievich

Dates

2010-06-20Published

2008-04-11Filed