METHOD OF PREPARING MIXTURE FOR PRODUCING CERAMIC BIODEGRADABLE MATERIAL Russian patent published in 2012 - IPC C04B35/447 A61L27/12 B82B3/00 

FIELD: chemistry.

SUBSTANCE: invention relates to medical material science and can be used in producing materials for trauma surgery and orthopaedics, maxillofacial surgery and dental surgery, as well as carriers for medicinal agents. The disclosed method involves synthesis of octacalcium phosphate from partially soluble calcium phosphate in an acetate buffer aqueous solution of CH₃COOH/CH₃COONa at temperature 55-65°C and pH 5.5-5.8, separating the residue, washing the residue, drying the residue and thermal treatment. The partially soluble compound used is brushite with moisture content 5-55% and the weight ratio of brushite/buffer solution is in the range of 1/80-1/100. Synthesis is 30-60 minutes long. Thermal treatment of the powder is carried out at 400-700°C for 1-2 hours by putting the powder into a furnace which is preheated to thermal treatment temperature. Brushite is pre-synthesised and the storage life of brushite after synthesis is 0.1-24 hours.

EFFECT: obtaining a calcium phosphate-based mixture with phase distribution homogeneity in the range of 20-40 nm for producing ceramic biodegradable material consisting of calcium pyrophosphate and tricalcium phosphate, with phase distribution homogeneity in the range of 50-100 nm.

2 cl, 1 ex, 1 tbl