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2 394 577

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IPC

A61K31/56(2006-01-01)

A61K31/196(2006-01-01)

A61P37/00(2006-01-01)

G09B23/28(2006-01-01)

(21) (22)

Application

2008151816/14, 2008-12-25

(24)

Start date

2008-12-25

(22)

Actual filing date

2008-12-25

(45)

Published

2010-07-20

(72)

Inventor

Zheleznova Alla DmitrievnaPanfilova Tat'Jana VladimirovnaSkachkov Mikhail Vasil'EvichKalinina Ol'Ga VjacheslavovnaBorisov Sergej DiljusovichFrolov Boris Aleksandrovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennaja Meditsinskaja Akademija Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju" Vpo Orgma Roszdrava)

METHOD OF PROTECTING POST-VACCINATION IMMUNITY TO TETANUS ANATOXIN AGAINST METHOTREXATE-INDUCED DEPRESSION Russian patent published in 2010 - IPC A61K31/56 A61K31/196 A61P37/00 G09B23/28

Abstract RU 2394577 C1

FIELD: medicine.

SUBSTANCE: invention relates to experimental medicine, and can be used for protection of post-vaccination immunity to tetanus anatoxin against methotrexate-induced depression. Method includes parenteral introduction of miliacin into experimental animal organism in dose 2 mg/kg of weight. Miliacin is introduced tree times daily to animals with formed post-vaccination immunity to tetanus anatoxin, subjected to immunodepressive impact of methotrexate cytostatic.

EFFECT: application of invention allows to protect formed post-vaccination immunity against immunodepressive impact of cytostatic due to anticatabolic action of miliacin.

5 dwg

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RU 2 394 577 C1

Authors

Zheleznova Alla Dmitrievna

Panfilova Tat'Jana Vladimirovna

Skachkov Mikhail Vasil'Evich

Kalinina Ol'Ga Vjacheslavovna

Borisov Sergej Diljusovich

Frolov Boris Aleksandrovich

Dates

2010-07-20—Published

2008-12-25—Filed