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IPC

A61K31/56(2006-01-01)

A61P39/00(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2014118652/15, 2014-05-07

(24)

Start date

2014-05-07

(22)

Actual filing date

2014-05-07

(45)

Published

2015-10-10

(72)

Inventor

Smoljagin Aleksandr IvanovichChajnikova Irina NikolaevnaFilippova Julija VladimirovnaPanfilova Tat'Jana VladimirovnaZheleznova Alla DmitrievnaFrolov Boris Aleksandrovich

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennaja Meditsinskaja Akademija" Ministerstva Zdravookhranenija Rossijskoj Federatsii Vpo Orgma Minzdrava Rossii/

AGENT FOR REDUCING SYSTEMIC PATHOLOGIC ENDOTOXINEMIA Russian patent published in 2015 - IPC A61K31/56 A61P39/00 A61P31/04

Abstract RU 2564918 C1

FIELD: medicine.

SUBSTANCE: what is presented is using pentacyclic triterpenoid miliacine as an agent to reduce systemic pathological endotoxinemia accompanying the salmonella infection.

EFFECT: pre-administration of miliacine has provided reducing blood endotoxins in the infected animals and the production of the inflammation mediators IL-6, IL-17, gamma-INF, but increasing the production of the proinflammatory cytokine IL-10; death of the infected animals has been decreased.

2 dwg

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RU 2 564 918 C1

Authors

Smoljagin Aleksandr Ivanovich

Chajnikova Irina Nikolaevna

Filippova Julija Vladimirovna

Panfilova Tat'Jana Vladimirovna

Zheleznova Alla Dmitrievna

Frolov Boris Aleksandrovich

Dates

2015-10-10—Published

2014-05-07—Filed