FIELD: medicine, immunology.
SUBSTANCE: invention proposes an agent enhancing the immunogenic properties of tetanus anatoxin (adjuvant). Invention proposes the vegetable triterpenic compound miliacin as an agent enhancing immunogenic properties of tetanus anatoxin. Agent enhances the immune response value in its applying as a vaccine preparation of tetanus anatoxin. The agent miliacin elicits its stimulating effect for both the first and repeated administration of vaccine that allows suggesting its possible applying for prophylactic vaccinations with tetanus anatoxin. Taking into account the high tolerance of miliacin in the broad range of its doses it is suggested its practical applying as an agent promoting to the enhanced formation of vaccinal immunity in prophylactic vaccinations with tetanus anatoxin.
EFFECT: valuable medicinal properties of agent.
6 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PROTECTING POST-VACCINATION IMMUNITY TO TETANUS ANATOXIN AGAINST METHOTREXATE-INDUCED DEPRESSION | 2008 |
|
RU2394577C1 |
| VACCINE AND METHOD FOR INCREASING IMMUNOGENICITY AND SPECIFIC ACTIVITY OF INFECTION PREVENTION AGENTS | 2020 |
|
RU2741834C1 |
| METHOD OF PRODUCTION OF ADJUVANT FOR VIRAL VACCINES | 2014 |
|
RU2545714C1 |
| METHOD OF PRODUCING ADJUVANT FOR VACCINE | 2014 |
|
RU2545717C1 |
| METHOD OF ESTIMATING ANTI-ERGOTYPIC RESPONSE IN EXPERIMENT | 2009 |
|
RU2423079C1 |
| COMBINED BACTERIAL MENINGITIS VACCINES TO BE INTRODUCED THROUGH MUCOUS MEMBRANE | 2003 |
|
RU2378008C2 |
| MICROFLUIDIZED COMPOSITION FOR INDUCTION OF SPECIFIC CYTOTOXIC T-LYMPHOCYTE IMMUNE RESPONSE AND ITS USING FOR DISEASE TREATMENT | 1995 |
|
RU2201253C2 |
| METHODS FOR INCREASING VACCINE EFFICIENCY BY INJECTING IL-4R ANTAGONIST | 2017 |
|
RU2753869C2 |
| IMMUNOGENIC COMPOSITIONS AND METHODS | 2008 |
|
RU2468034C2 |
| USE OF PEPTIDE THAT ENHANCES SECRETION OF SOMATOTROPIC HORMONE AS VACCINE ADJUVANT | 2017 |
|
RU2768134C2 |
