FIELD: medicine.
SUBSTANCE: there is offered a method for measuring degree of human chromosome fragility. For three days running, blood is drawn threefold from the ulnar vein for lymphocyte cultivation and preparations of metaphase chromosome specimen and chromosome analysis; the degree of chromosome aberration is measured to calculate a genetic destruction index (GDI).
EFFECT: method allows for well-timed measurement of the degree of chromosome fragility to prescribe an adequate correcting approach to decrease GDI in each specific case.
3 ex
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Authors
Dates
2010-07-27—Published
2009-01-30—Filed