METHOD OF SIMPLIFIED ACTIVITY RATING OF NUCLEOLAR-FORMING CHROMOSOME REGIONS Russian patent published in 2010 - IPC G01N33/48 

Abstract RU 2390021 C1

FIELD: medicine.

SUBSTANCE: to analyse the activity of NFC regions, a blood sample is drawn from ulnar vein to be cultivated to make metaphase chromosome preparations. Thereafter, the chromosome preparations are analysed to investigate the activity of the NFC regions in cells and to calculate an NFC regions activity index (NFCR AI). If the NFCR AI is within 0.064 to 0.070, the activity of the NFC regions is considered as normal, the values 0.058 to 0.063 show hyperactivity, and 0.071 to 0.075 - hypoactivity; if the NFCR AI is 0.057 and lower, the activity is sharply increased, while the NFCR AI 0.076 and higher indicate the sharply lowered activity. Application of the method allows improving accuracy and availability of determining early changes of the activity of the NFC regions in cells.

EFFECT: well-timed and adequate prescription of a corrective approach to normalise the NFCR AI in each specific case allows optimising genetic processes and ensures eugenesis in mothers-to-be.

5 ex

Similar patents RU2390021C1

Title Year Author Number
METHOD OF ESTIMATION OF ACTIVITY OF NUCLEOUS ORGANISER REGIONS OF CHROMOSOMES IN CELLS 2007
  • Medvedev Il'Ja Nikolaevich
  • Amelina Irina Valer'Evna
  • Bespartochnyj Boris Dmitrievich
RU2343483C1
METHOD OF GENOME STABILITY TEST 2009
  • Medvedev Il'Ja Nikolaevich
  • Amelina Irina Valer'Evna
  • Bespartochnyj Boris Dmitrievich
RU2405152C1
METHOD OF EVALUATING ADAPTIVE ABILITIES OF HUMAN GENOME 2009
  • Medvedev Il'Ja Nikolaevich
  • Amelina Irina Valer'Evna
  • Bespartochnyj Boris Dmitrievich
RU2391662C1
METHOD FOR MEASURING DEGREE OF HUMAN CHROMOSOME FRAGILITY 2009
  • Medvedev Il'Ja Nikolaevich
  • Amelina Irina Valer'Evna
  • Bespartochnyj Boris Dmitrievich
RU2395809C1
METHOD OF DETERMINATION OF GENETIC STABILITY OF HUMAN CHROMOSOMES 2007
  • Medvedev Il'Ja Nikolaevich
  • Amelina Irina Valer'Evna
  • Bespartochnyj Boris Dmitrievich
RU2343478C1
METHOD OF BIOLOGICAL AGE NORMALISATION FOR PERSONS WITH METABOLIC SYNDROME 2006
  • Medvedev Il'Ja Nikolaevich
  • Bespartochnyj Boris Dmitrievich
RU2332207C2
METHOD OF VESSEL ENDOTELIAL LINING STABILISATION FOR PATIENTS SUFFERING FROM METABOLIC SYNDROME 2006
  • Medvedev Il'Ja Nikolaevich
  • Bespartochnyj Boris Dmitrievich
RU2329805C2
METHOD FOR PREDICTING UNFAVORABLE COURSE OF PYOSEPTIC DISEASE DEVELOPMENT 1998
  • Ishmukhametov G.Sh.
  • Viktorov V.V.
  • Viktorova T.V.
  • Mironov P.I.
  • Khusnutdinova Eh.K.
RU2143690C1
METHOD OF ATOPIC DERMATITIS PREDICTION IN INFANTS 2008
  • Ratnikova Svetlana Jur'Evna
  • Zhukova Tat'Jana Pavlovna
  • Koneva Tat'Jana Gennad'Evna
RU2353927C1
METHOD FOR ESTIMATION OF LEVEL OF COMPENSATORY-ADAPTIVE AND ADAPTATION CAPABILITIES OF COSMONAUTS BODIES 2015
  • Kosyakova Nadezhda Viktorovna
  • Lyapunova Nataliya Alekseevna
  • Mandron Irina Aleksandrovna
  • Tsvetkova Tatyana Gennadevna
  • Markin Andrej Arkadevich
  • Nichiporuk Igor Aleksandrovich
  • Kuzichkin Dmitrij Sergeevich
RU2624860C1

RU 2 390 021 C1

Authors

Medvedev Il'Ja Nikolaevich

Amelina Irina Valer'Evna

Bespartochnyj Boris Dmitrievich

Dates

2010-05-20Published

2009-01-30Filed