FIELD: chemistry; biochemistry.
SUBSTANCE: invention relates to biotechnology, specifically to obtaining antigenic peptides and can be used in medicine. A biologically active peptide with the following amino acid sequence is obtained: Ala-Tyr-Ala-Cys-Asn-Thr-Ser-Thr-Leu-Lys-Val-Arg- Arg-Ala-Ile-Glu-Gln-Leu-Ala. The obtained peptide can stimulate formation of antibodies which are specific to tumour-associated survivin protein.
EFFECT: invention enables detection of survivin in tissue using an immunohistochemical technique in order to diagnose cancerous growths.
2 dwg, 1 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PEPTIDE STIMULATING FORMATION OF SPECIFIC ANTIBODIES AGAINST OLIGOMERIC FORM OF NUCLEOPHOSMIN IN TUMOUR CELLS | 2009 |
|
RU2401275C1 |
| PEPTIDE WITH PROTECTIVE ACTION AGAINST ALZHEIMER'S DISEASE | 2008 |
|
RU2372355C1 |
| PEPTIDE STIMULATING FORMATION OF SPECIFIC ANTIBODIES AGAINST MONOMERIC FORM OF NUCLEOPHOSMIN IN TUMOUR CELLS | 2009 |
|
RU2401274C1 |
| PEPTIDE HAVING CURATIVE EFFECT AGAINST ALZHEIMER DISEASE | 2014 |
|
RU2558242C1 |
| PEPTIDE HAVING THERAPEUTIC EFFECT AGAINST ALZHEIMER'S DISEASE | 2018 |
|
RU2677296C2 |
| GLP-1 PEPTIDE HAVING ATTACHED OLIGOSACCHARIDE CHAIN | 2008 |
|
RU2539829C2 |
| PEPTIDE WITH TREATMENT ACTION AGAINST ALZHEIMER'S DISEASE | 2016 |
|
RU2626972C2 |
| GLYCATED PEPTIDE GLP-1 | 2009 |
|
RU2543157C2 |
| METASTIN DERIVATIVES AND USE THEREOF | 2007 |
|
RU2454425C2 |
| GLP-1 ANALOGUE DERIVATIVE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND THEREOF APPLICATION | 2010 |
|
RU2565536C2 |
