METHOD OF PRODUCING PARTIALLY FLUORINATED AROMATIC AMINES Russian patent published in 2010 - IPC C07C209/62 C07C209/74 C07C211/52 C07C231/12 

FIELD: chemistry.

SUBSTANCE: method of producing partially fluorinated aromatic amines which contain at least one hydrogen atom in the ortho-position of the amino group, having general formula 1, , X = F (1a) or H (1b), is distinguished by that pentafluoroaniline is functionalised on the amino group through treatment with a derivative of aliphatic or aromatic mono- or dicarboxylic acid to obtain the corresponding derivative of pentafluoroaniline as a substrate which undergoes hydrodefluorination under the effect of a reducing metal in the presence of a proton source and in the presence of a catalyst - complex compound of nickel and/or cobalt with ligands selected from heterocyclic nitrogen-containing compounds or phosphorus-containing compounds in a medium of an aprotic dipolar solvent with subsequent alkaline or acid hydrolysis of the reaction mixture to form the corresponding amine.

EFFECT: improved method.

7 cl, 1 dwg, 6 tbl, 44 ex