FIELD: medicine.
SUBSTANCE: invention relates to field of veterinary virology. Virus-vaccine contains antigen material from attenuated "ARRIAH" strain of sheep pox virus (SPV), Variola virus ovinum, fam. Poxviridae, subfam. Chordopoxvirinae, genus Capripoxvirus, obtained in culture of goat gonad cells Ch-91 with infectious activity not less than 5.5 lg TCD50/cm 3, deposited in collection of FSI VGNKI under registration number (reference) "ARRIAH", and stabilising agent. Additionally vaccine contains antigen material from attenuated strain "ARRIAH 2003" of goat pox virus (GPV) Variola virus caprinum, fam. Poxviridae, subfam. Chordopoxvirinae, genus Capripoxvirus, obtained in culture of goat gonad cells Ch-91 with infectious activity not less than 5.5 lg TCD50/cm 3 and deposited in collection of FSI VGNKI under registration number (reference) "ARRIAH 2003" - DEP, with ratio, wt %: antigen material from attaenuated strain "ARRIAH" SPV 40.0-45.0, antigen material from attenuated strain "ARRIAH 2003" GPV - 40.0-45.0, stabilising agent - the remaining part.
EFFECT: virus-vaccine is sterile, specific, possesses high immunogenic activity, is harmless for sheep and goat.
4 dwg, 9 tbl, 8 ex
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Authors
Dates
2010-11-10—Published
2009-04-21—Filed