FIELD: medicine.
SUBSTANCE: invention refers to veterinary virology and biotechnology. As an active substance, a virus-vaccine contains antigen material of attenuated "VNIISZH 2003" strain of goat-pox virus (GPV) Variola vims caprmum of Poxviridae fam., Chordopoxvirinae subfam., Capripoxvirus genus deposited in collection of FGU "VGNKI", VNIISZH 2003 registration No. (reference) - DEP, in the effective amount. The strain is reproduced in a Ch-91 cell culture for 5-7 days and is collected in titre 5.5 lg "ТЦД"50/cm3 to 7.0 lg "ТЦД"50/cm3. The strain preserves initial characteristics when passing the Ch-91 cell culture for 35 passages.
EFFECT: virus-vaccine protects immunised animals from contact infection by epizootic goat-pox virus circulating in the territory of Russia.
4 dwg, 8 cl, 7 tbl, 8 ex
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Authors
Dates
2010-08-20—Published
2008-12-04—Filed