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2 404 971

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IPC

C07D215/18(2006-01-01)

A61K31/47(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2008147273/04, 2008-12-02

(24)

Start date

2008-12-02

(22)

Actual filing date

2008-12-02

(45)

Published

2010-11-27

(72)

Inventor

Zharov Aleksej NikolaevichSavost'Janov Sergej VladimirovichTagachenkov Andrej AlekseevichIvanov Andrej SergeevichFedorov Vladimir EgorovichPerminov Sergej Vladimirovich

(73)

Holder

Zao

NOVEL QUINOLINE DERIVATIVES, SYNTHESIS METHOD THEREOF, USE THEREOF IN TREATING MYCOBACTERIAL INFECTIONS, PHARMACEUTICAL COMPOSITION BASED ON SAID DERIVATIVES Russian patent published in 2010 - IPC C07D215/18 A61K31/47 A61P31/06

Abstract RU 2404971 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel quinoline derivatives of general formula II, where R¹ denotes halogen, R² denotes halogen, R³ denotes hydroxy, R⁴, R⁵ denote C₁-C₃-alkyl, R⁶ denotes aryl, R⁷ denotes aryl, n=1 or 2, as well as to pharmaceutically acceptable acid or base addition salts thereof, having activity towards mycobacteria. The invention also relates to a method for synthesis of formula II compounds.

EFFECT: obtaining novel quinoline derivatives with useful biological activity.

3 cl, 4 tbl, 5 ex

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RU 2 404 971 C2

Authors

Zharov Aleksej Nikolaevich

Savost'Janov Sergej Vladimirovich

Tagachenkov Andrej Alekseevich

Ivanov Andrej Sergeevich

Fedorov Vladimir Egorovich

Perminov Sergej Vladimirovich

Dates

2010-11-27—Published

2008-12-02—Filed