FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and aims at preventing and treating infectious diseases caused by mycobacterial infections. One embodiment is compound N'-hydroxy-N-(4-isopentyl-2-methylphenyl)formimidamide, characterized by the following structural formula:
.
Other embodiments are use of said compound for treating and/or preventing an infectious disease in a subject caused by a mycobacterial infection, and use of said compound to produce a pharmaceutical composition for treating and/or preventing an infectious disease caused by a mycobacterial infection. Also provided is a pharmaceutical composition for treating and/or preventing an infectious disease caused by a mycobacterial infection, comprising an effective amount of said compound and at least one pharmaceutically acceptable excipient.
EFFECT: using the group of inventions enables providing more effective prevention and treatment of diseases associated with the mycobacterial infection, particularly tuberculosis.
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| Title | Year | Author | Number |
|---|---|---|---|
| ANTITUBERCULOSIS REMEDY | 2017 |
|
RU2756208C2 |
| SANFETRINEM OR ITS SALT OR COMPLEX ESTER FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTION | 2018 |
|
RU2757272C2 |
| NEW COMPOUNDS | 2018 |
|
RU2783078C2 |
| QUINOLINE DERIVATIVES, PARTICULARLY 5,6,7-SUBSTITUTED 1-(2-CHLOROQUINOLIN-3-YL)-4-DIMETHYLAMINO-2-(NAPHTHALEN-1-YL)-1-PHENYLBUTAN-2-OLES, METHOD FOR PREPARING AND USING COMPOUNDS | 2011 |
|
RU2486175C2 |
| METHOD FOR PREPARING HIGH-BIOAVAILABILITY RIFABUTIN COMPOSITION, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATING MYCOBACTERIOSIS | 2013 |
|
RU2520603C1 |
| NOVEL QUINOLINE DERIVATIVES, SYNTHESIS METHOD THEREOF, USE THEREOF IN TREATING MYCOBACTERIAL INFECTIONS, PHARMACEUTICAL COMPOSITION BASED ON SAID DERIVATIVES | 2008 |
|
RU2404971C2 |
| β-CARBOLINE DERIVATIVES, POSSESSING ANTI-TUBERCULOSIS ACTIVITY, THEIR APPLICATION FOR MEDICATION MANUFACTURING, METHOD OF THEIR SYNTHESIS, AS WELL AS NOVEL METHODS OF TREATMENT WITH THEIR APPLICATION | 2010 |
|
RU2419431C1 |
| PHARMACEUTICAL COMPOSITION AND KIT FOR TREATING BACTERIAL INFECTIONS | 2011 |
|
RU2496475C2 |
| PREPARATIONS, CONTAINING HUMAN ANTIBODIES APPLIED IN TREATMENT OF MICROBACTERIAL INFECTIONS | 2003 |
|
RU2350352C2 |
| MYCOBACTERIUM TUBERCULOSIS VACCINE | 2009 |
|
RU2473365C1 |
