FIELD: medicine.
SUBSTANCE: hereby is described new method of obtaining highly densified and at least partly but preferably completely or almost completely hydrated ceramic material designed for use in pharmaceutical composition manufacture, in particular for controlled release of one or more therapeutic, prophylactic and/or diagnostic compound. Method includes concomitant hydration and densification stage of biologically resolving and hydrating ceramic material such as calcium sulfate.
EFFECT: invention also belongs to compositions containing such ceramic highly densified material pharmaceutical composition can be used for targeted and controlled prolonged local release of active compounds, eg anticancer remedies, thus minimising side effects' range and gravity due to local concentration's temporally optimised dynamics profile.
77 cl, 8 dwg, 9 ex, 5 tbl
Authors
Dates
2010-12-10—Published
2007-03-14—Filed