FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to gastroenterology and therapy, can be used to update a prediction of clinical course of the gastric ulcer (GU). It involves the evaluation of an ulcer defect, Helicobacter infection content, and hemolytic resistance parametres. An individual dynamics of ulcer defect cicatrisation of a wall of stomach is calculated by formula: Cicatrisation dynamics = 0.139831+0.853145·S_prior - 0.0000181334· tlat-0.0221184· Kmax - 0.000185502·HP, where S_prior is the defect area prior to the initiation of treatment, Kmax is a maximum erythrocyte hemolysis rate constant, tlat is latent hemolysis time, HP is the Helicobacter infection content. And if the derived coefficient is equal to or less than 0.6, ulcer healing within a therapeutic standard time limit is predicted, if it exceeds 0.6, prolonged gastric ulcer healing is supposed.
EFFECT: method allows to estimate the ulcer defect cicatrisation dynamics even prior to the initiation of treatment that in turn allows to optimise drug therapy.
1 tbl, 1 dwg
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTION OF ULCER CICATRISATION RATE IN PATIENTS WITH UNCOMPLICATED GASTRIC ULCER | 2014 |
|
RU2572725C2 |
METHOD FOR PREDICTING THE EXACERBATIONS OF GASTRODUODENAL ULCER ASSOCIATED WITH HELICOBACTER PYLORI | 2017 |
|
RU2664449C1 |
METHOD FOR ENDOSCOPIC TREATMENT OF GASTRODUODENAL ULCER | 2005 |
|
RU2295957C1 |
METHOD FOR PREDICTING THE FLOW OF GASTRIC AND DUODENAL ULCEROUS DISEASE | 2003 |
|
RU2246731C1 |
PREPARATION FOR TREATING DUODENAL ULCEROUS DISEASE AT HELICOBACTER ERADICATION | 2002 |
|
RU2225719C2 |
THERAPY METHOD FOR SLUGGISH ULCERS AND EROSIONS IN GASTRODUODENAL SYSTEM | 2003 |
|
RU2261091C2 |
SPLENOTHERAPY METHOD FOR TREATING GASTRODUODENAL ULCERS | 2001 |
|
RU2179858C1 |
METHOD FOR ENDOSCOPIC TREATMENT OF EROSIVE AND ULCERATIVE LESIONS OF THE STOMACH AND DUODENUM | 2021 |
|
RU2763754C1 |
METHOD FOR PREDICTING RISK OF DEVELOPING COMPLICATED GASTRIC ULCER BASED ON DETERMINING EXPRESSION LEVEL OF MICRORNA-155 | 2024 |
|
RU2823477C1 |
METHOD OF GASTRIC ULCER TREATMENT, ASSOCIATED WITH HELICOBACTER INFECTION | 2007 |
|
RU2365371C1 |
Authors
Dates
2010-12-20—Published
2008-11-24—Filed