METHOD FOR PREDICTION OF GASTRIC ULCER CICATRISATION RATE Russian patent published in 2010 - IPC A61B10/00 G01N33/48 

Abstract RU 2406448 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to gastroenterology and therapy, can be used to update a prediction of clinical course of the gastric ulcer (GU). It involves the evaluation of an ulcer defect, Helicobacter infection content, and hemolytic resistance parametres. An individual dynamics of ulcer defect cicatrisation of a wall of stomach is calculated by formula: Cicatrisation dynamics = 0.139831+0.853145·S_prior - 0.0000181334· tlat-0.0221184· Kmax - 0.000185502·HP, where S_prior is the defect area prior to the initiation of treatment, Kmax is a maximum erythrocyte hemolysis rate constant, tlat is latent hemolysis time, HP is the Helicobacter infection content. And if the derived coefficient is equal to or less than 0.6, ulcer healing within a therapeutic standard time limit is predicted, if it exceeds 0.6, prolonged gastric ulcer healing is supposed.

EFFECT: method allows to estimate the ulcer defect cicatrisation dynamics even prior to the initiation of treatment that in turn allows to optimise drug therapy.

1 tbl, 1 dwg

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Authors

Pluzhnikov Jurij Dmitrievich

Chernov Jurij Nikolaevich

Rezvan Sergej Grigor'Evich

Pluzhnikov Dmitrij Jur'Evich

Romanovskaja Julija Vladimirovna

Dates

2010-12-20Published

2008-11-24Filed