FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to chemical-pharmaceutical industry, and concerns a transbuccal delivery system including a matrix of: (a) an effective amount of one or more active ingredients; (b) an amount of one or more polyethylene glycols or their derivatives of molecular weight within 1000 to 8000, sufficient to maintain the required hardness and matrix disintegration; (c) 0.05-2 wt % of one or more suspending agents of matrix mass; (d) 0.05-2 wt % of one or more liquidity agents of matrix mass; and (c) 0.05-2 wt % of one or more sweeteners of matrix mass.
EFFECT: development of the transbuccal delivery system to be prepared conventionally, preparation of a dry powder and enabled pressing with applying a common device for tablets manufacturing.
25 cl, 4 ex, 6 dwg, 5 tbl
