FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to compounds of formula (I) and to their pharmaceutically acceptable salts. In formula (I)
,
R1 represents hydrogen; each of R2, R3, R4, R5, R4 and R5 independently represents hydrogen or C1-C6alkyl; x equals 0 or 1; Arepresents oxygen, sulphur, S(O) or S(O)2; D represents oxygen or NR6; W represents bond or CR6aR6b; n equals integer number from 0 to 2; R6 represents hydrogen, C1-C6alkyl, C1-C6alkoxycarbonyl; Y represents bond, CR2eR2f; R2a, R2b, R2c, R2d, R2e, R2f, R6a and R6b represent independently hydrogen or C1-C6alkyl; R7a represents hydrogen or NHR7b; R7b represents hydrogen, C1-C6alkyl, C1-C6alkoxycarbonyl; R7 represents 6-12-member aromatic ring system, probably substituted with halogen, trifluoromethyl, C1-C6alkyl. Invention also relates to pharmaceutical composition, containing invention compound, as well as to
compounds 
; 
, where R represents hydrogen or benzyl.
EFFECT: obtaining compounds, which possess properties of β2-adrenoreceptors agonist.
15 cl, 2 tbl, 50 ex
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