FIELD: medicine, pharmaceutics.
SUBSTANCE: medicinal composition for treating cerebral ischemia and senile dementia contains 1-10 weight parts of ginseng root, 1-10 weight parts of ginkgo leaves, 0.05-0.5 weight parts of saffron snouts and 5-10 weight parts of soya bean; said ginseng root, ginkgo leaves, saffron snouts and soya bean can be presented in the form of raw vegetable materials or extracts prepared by extraction of the raw vegetable material in the same amounts. At least double amount of 60-80 % ethanol is added to ginkgo leaves, and immersing extraction is carried out at 50-70°C at least once to produce liquid extracts; the liquid extracts are mixed and concentrated to enable relative density of the produce liquid concentrate to reach approximately 1.05; water is added to the liquid concentrate, and the prepared mixture is filtered to produce a filtrate; the filtrate is chromatographed on polar macroporous adsorption styrene resin in a protonation form; resin and drug substances are eluted with water and 60% ethanol; an aqueous eluent is discharged, while an ethanol containing eluent is collected and concentrated to eliminate alcohol odour and to produce a concentrated eluent; water is added to the concentrated eluent, and said mixture is filtered to prepare another filtrate; the filtrate is chromatographed on weakly polar macroporous adsorption styrene resin; resin and drug substances are eluted with water, 15% ethanol and 60% ethanol, respectively; the aqueous eluent and 15% ethanol eluent are discharged, while 60% ethanol eluent is collected. The inventions allow implementing specified object matters.
EFFECT: preparation of the composition for treating cerebral ischemia and senile dementia.
12 cl, 5 ex, 12 tbl
