1-(2-ISOPROPOXYETHYL)-2-THIOXO-1,2,3,5-TETRAHYDRO-PYRROLO[3,2-d]PYRIMIDIN-4-ONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF Russian patent published in 2011 - IPC C07D487/04 A61K31/519 A61P25/16 

Abstract RU 2409578 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel chemical compound - 1-(2-isopropoxyethyl)-2-thioxo-1,2,3,5-tetrahydro-pyrrolo [3,2-d]pyrimidin-4-one and pharmaceutically acceptable salts thereof, a pharmaceutical composition containing said compounds and use thereof. Disclosed compound has myeloperoxidase enzyme inhibiting properties.

EFFECT: compounds are especially useful in treating and preventing neuroinflammatory disorders such as Parkinson's disease, cardiovascular disorders and respiratory disorders.

3 cl, 1 tbl, 33 ex

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RU 2 409 578 C2

Authors

Begevig Anders

Lo-Al'Fredsson Ivonne

Pivonka Donal'D

Tiden Anna-Karin

Dates

2011-01-20Published

2005-12-05Filed