FIELD: medicine.
SUBSTANCE: modified virus-like particle (VLP) includes hybrid protein which consists of AP205 bacteriophage protein and any antigen. Also, a composition including VLP, being a derivative of RNA-containing AP205 bacteriophage is described. Besides, the invention describes a method for producing said VLP. Modified VLP of the present invention is applicable for producing compositions for inducing immune response for prevention or treatment of diseases, disorders, including infectious diseases, allergies, cancer and drug addiction.
EFFECT: offered group of inventions can be used in medicine, immunology, virology and molecular biology.
35 cl, 3 dwg, 1 tbl, 26 ex
| Title | Year | Author | Number |
|---|---|---|---|
| INTERLEUKIN-1 CONJUGATES AND THEIR APPLICATION | 2006 |
|
RU2441067C2 |
| CAT ALLERGEN FUSED PROTEIN AND APPLICATION THEREOF | 2006 |
|
RU2414239C2 |
| ANTIGEN MOLECULAR MASSIFS | 2003 |
|
RU2324704C2 |
| MODIFIED VIRUS PARTICLES OF CUCUMBER MOSAIC VIRUS | 2015 |
|
RU2706970C2 |
| COMPLETED VIRUS-LIKE PARTICLES | 2004 |
|
RU2375076C2 |
| VIRUS-LIKE PARTICLES CONTAINING TARGET PROTEINS FUSED WITH COAT PROTEINS OF PLANT VIRUSES | 2010 |
|
RU2571223C2 |
| CONJUGATE OF ANGIOTENSIN PEPTIDE COMPONENT WITH CARRIER, VACCINE COMPOSITION, METHOD OF ANIMAL IMMUNISATION AND METHOD OF TREATMENT OR PREVENTION OF PHYSICAL DISORDER RELATED TO ANGIOTENSIN SYSTEM ACTIVATED BY RENIN | 2002 |
|
RU2350622C2 |
| COMPOSITIONS AND METHODS FOR TREATING CYTOMEGALOVIRUS | 2012 |
|
RU2737530C1 |
| HOMODIMER PROTEIN CONSTRUCTION | 2011 |
|
RU2624041C2 |
| CONJUGATES OF PEPTIDE Melan-A, VIRUS-LIKE PARTICLE ANALOGUE | 2004 |
|
RU2351362C2 |
