FIELD: medicine.
SUBSTANCE: viral vaccine contains cell-associated turkey herpes virus (THV) of "Vladimir" strain, cattle blood serum (CBS) and dimethylsulfoxide (DMSO) in ratio, wt %: 60.0÷80.0; 15.0÷25.0 and 5.0÷15.0 respectively. Strain is deposited in FGI VGNKI collection of microorganisms under registration number (reference) "Vladimir No 124-DEP" THV (further "Strain"). Strain is reproduced in culture of SPF-chicken embryo fibroblast cells (CFE) and reaches titre 3.5·106 PFU/cm3, for vaccine manufacturing used is suspension of infected CFE cells with titre not lower than 5.5·105 PFU/cm3.
EFFECT: viral vaccine possesses high immunogenic activity, protects immunised population of poultry against infection of epizootic MDV, circulating on the territory of Russia.
6 cl, 5 ex, 3 tbl
Title | Year | Author | Number |
---|---|---|---|
INDUSTRIAL STRAIN "VLADIMIR" OF TURKEY HERPESVIRUS FOR VIRAL VACCINE FOR MAREK'S DISEASE | 2007 |
|
RU2336303C1 |
VIRUS-VACCINE AGAINST MARECK'S DISEASE AND METHOD OF ITS PREPARING | 1999 |
|
RU2144378C1 |
VIRUS VACCINE AGAINST MAREK'S DISEASE | 2001 |
|
RU2205660C2 |
METHOD FOR PREPARING VIRUS-VACCINE AGAINST MARECK'S DISEASE | 2001 |
|
RU2209635C2 |
BIVALENT VACCINE AGAINST MARECK'S DISEASE AND METHOD OF ITS PREPARING | 1999 |
|
RU2144377C1 |
MARECK'S DISEASE VIRUS STRAIN 3004/ 109 FOR VACCINE PREPARATION PREPARING | 2001 |
|
RU2199583C1 |
DRY VIRUS-VACCINE AGAINST MARECK'S DISEASE AND METHOD OF ITS PREPARING | 1999 |
|
RU2144376C1 |
METHOD FOR OBTAINING BIVALENT VACCINE AGIANTS MAREK'S DISEASE | 2000 |
|
RU2203681C2 |
TURKEY HERPES VIRUS STRAIN "VNIIZZH/N 110" FOR PREPARING VACCINE AGAINST MARECK'S DISEASE | 1999 |
|
RU2144562C1 |
METHOD OF PRODUCTION OF DRY POLYVALENT VIRUS-VACCINE FOR MAREK'S DISEASE PREVENTION AND DRY POLYVALENT VIRUS-VACCINE FOR MAREK'S DISEASE PREVENTION | 2005 |
|
RU2327488C2 |
Authors
Dates
2011-01-27—Published
2009-06-29—Filed