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(19)

RU

(11)

2 410 384

(13)

C2

(51)

IPC

C07D401/12(2006-01-01)

A61K31/496(2006-01-01)

A61P9/04(2006-01-01)

(21) (22)

Application

2007101619/04, 2005-06-16

(24)

Start date

2005-06-16

(22)

Actual filing date

2005-06-16

(45)

Published

2011-01-27

(72)

Inventor

Morgan Brehdli P.Mutsi AleksLju Pu-PingKrejnek EhrikaTokhimoto ToddMorgans Dehvid

(73)

Holder

Tsitokinetiks, Ink.

COMPOUNDS, COMPOSITIONS AND METHODS OF THEIR APPLICATION Russian patent published in 2011 - IPC C07D401/12 A61K31/496 A61P9/04 

Abstract RU 2410384 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to novel substituted derivatives of urea, which possess properties of selective modulator of cardiac sarcomere, for instance, enhance action of cardiac myosin. Novel compounds are selected from compounds corresponding to structural formulas: .

EFFECT: compounds can be used in treatment for heart failure, in particular in treatment of systolic heart failure and congestive heart failure.

30 cl, 17 ex

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RU 2 410 384 C2

Authors

Morgan Brehdli P.

Mutsi Aleks

Lju Pu-Ping

Krejnek Ehrika

Tokhimoto Todd

Morgans Dehvid

Dates

2011-01-27—Published

2005-06-16—Filed

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