FIELD: medicine.
SUBSTANCE: invention relates to biotechnology and represents antibody or its fragment, which is able to bind with homologue 10 of protein Frizzled (FZD10), such as monoclonal mouse antibody, hybrid antibody, chimeric and humanised antibody. Also claimed are hybridoma clones, producing antibody, as well as method of treatment of prevention of FZD10-associated disease; method of diagnostics or prediction of FZD10-associated disease; method of visualisation in vivo FZD10 in a subject; pharmaceutical composition and set, containing antibody.
EFFECT: treatment with claimed antibodies makes it possible to improve clinical outcome in case of diseases associated with homologue to of protein Frizzled.
44 cl, 45 dwg, 8 ex
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