METHOD OF LIQUID SUBSTANCE INTRODUCTION IN MICROCAPSULES AND RELATED DEVICE FOR IMPLEMENTATION THEREOF Russian patent published in 2011 - IPC A61M37/00 

FIELD: medicine.

SUBSTANCE: group of inventions refers to biotechnology. A method involves microcapsule supply in a liquid flow onto an output of a microchannel plate 2. The diametre of its channels is less than the size of microcapsules which are kept on the input of the microchannel plate 2 after liquid drainage therethrough. A microneedle lattice 3 is moved to pierce a microcapsule enclosure and to introduce a liquid substance. Thereafter, the filled microcapsules are removed by changing the liquid flow direction through the microchannel plate 2 by a reverse one. The device comprises a microchannel plate 2, a channel 1 with a microcapsule containing liquid, a microneedle lattice 3 and a liquid substance container 4. The lattice 3 is coaxial to the microchannel plate 2. The microneedles are connected with the liquid substance container 4. The channel 1 comprises a microchannel plate 2, a microneedle lattice 3, a piston assembly 5 and valves 8, 9 for maintaining single-direction microcapsule containing liquid motion through the microchannel plate 2. The lattice 3 is movable towards the microchannel plate 2 by a distance of microcapsule enclosure piercing.

EFFECT: inventions provide a continuous process of liquid substance introduction simultaneously in a great number of microcapsules.

2 cl, 4 dwg