FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to chemical-pharmaceutical industry and deals with elaboration of method of obtaining blood-substituting composition on two high pressure desintegrators from the mixture of two perfluorocarbons, quickly excreted (C8-C10) and(or) slowly excreted (C11-C12), is emulsified with proxalon-268 from 0.2% to 20% with molecular weight 6-12 thousand Da, with further addition of acceptable electrolyte solution, with formation of fine dispersion emulsion with the average particle size 30-120 nm. Method is realised by homogenisation of obtained mixture on two high pressure homogenisers with two or four extrusion devices of homogenisers.
EFFECT: method makes it possible to obtain highly stable perfluorocarbonic emulsions, which possess lower reactogenicity.
12 cl, 6 ex, 1 tbl, 1 dwg
