FIELD: medicine.
SUBSTANCE: invention relates to experimental medicine, toxicology and deals with treatment and prevention of poisoning with phosphorus organic insecticides (POI). For this purpose carboxym and atropine are introduced to experimental animals in doses 2-3 time lower than in separate introduction.
EFFECT: method ensures increase of protective preventive efficiency in animals in experiment by 6-11 times, also due to allosteric exponentiation, which serves the base for further development of effective and safe POI antidote for people.
7 ex, 10 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF TREATING AND PREVENTING ORGANOPHOSPHOROUS INSECTICIDE POISONING | 2019 |
|
RU2705370C1 |
| HYDROCHLORIDES OF SUBSTITUTED 2-[(DIMETHYLAMINO)METHYL]ARYLDIMETHYL CARBAMATES EXHIBITING ANTICHOLINESTERASE ACTIVITY | 2020 |
|
RU2754133C1 |
| (1-METHYLPIPERIDIN-4-YL)-2-PROPYL PENTANOATE HYDROCHLORIDE, HAVING CHOLINOLYTIC AND ANTICONVULSANT ACTIVITY | 2019 |
|
RU2714135C1 |
| REMEDY FOR TREATING THE CASES OF POISONING WITH M- CHOLINOLYTIC AGENTS | 0 |
|
SU1703110A1 |
| THERAPEUTIC PREPARATION AT SPASMODIC SYNDROME | 2001 |
|
RU2191017C1 |
| COMBINED MEDICATION FOR WEIGHT-REDUCING TREATMENT | 2004 |
|
RU2363458C2 |
| METHOD OF DETERMINATION OF PESTICIDES AND DRUGS WITH ANTICHOLINESTERASE EFFECT | 0 |
|
SU1745769A1 |
| METHOD FOR PREVENTING ACUTE EXPOSURE TO ORGANOPHOSPHATES | 2013 |
|
RU2555764C1 |
| RECOMBINANT PLASMID DNA OF PFUSE/SCFV47FC, INTENDED FOR PRODUCING SINGLE-CHAIN ANTIBODY FUSED WITH HUMAN IMMUNOGLOBULIN CONSTANT FRAGMENT INACTIVATING PARAOXONE PESTICIDE | 2019 |
|
RU2732835C1 |
| COMPLEX CONNECTION OF 5-HYDROXY-3,6-DIMETHYLURACYL WITH SUCCINIC ACID EXHIBITING MEMBRANE-STABILIZING ACTIVITY AND METHOD OF ITS PRODUCTION | 2016 |
|
RU2631238C1 |
