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2 714 135

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(51)

IPC

C07D295/03(2006-01-01)

A61K31/445(2006-01-01)

A61P25/08(2006-01-01)

A61P21/02(2006-01-01)

(21) (22)

Application

2019137931, 2019-11-22

(24)

Start date

2019-11-22

(22)

Actual filing date

2019-11-22

(45)

Published

2020-02-12

(72)

Inventor

Bespalov Aleksandr YakovlevichProkopenko Lyubov IvanovnaGorchakova Tatyana LeonidovnaKozlov Viktor KonstantinovichPetrov Aleksandr NikolaevichZajtseva Mariya AnatolevnaMelekhova Aleksandra SergeevnaBelskaya Alisa VladimirovnaMelnikova Margarita ViktorovnaIvanov Maksim Borisovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Toksikologii Federalnogo Mediko-Biologicheskogo Agentstva"

(1-METHYLPIPERIDIN-4-YL)-2-PROPYL PENTANOATE HYDROCHLORIDE, HAVING CHOLINOLYTIC AND ANTICONVULSANT ACTIVITY Russian patent published in 2020 - IPC C07D295/03 A61K31/445 A61P25/08 A61P21/02

Abstract RU 2714135 C1

FIELD: chemistry.

SUBSTANCE: invention relates to 1-methylpiperidin-4-yl 2-propyl pentanoate hydrochloride of formula I, having cholinolytic and anticonvulsant activity.

(I)

EFFECT: claimed agent provides considerable reduction of intensity and reduced duration of toxic convulsive syndrome, as well as reduced mortality in acute poisoning with cholinesterase inhibitors, particularly carbamates, by using the claimed substance as a specific antidote.

1 cl, 3 tbl, 5 ex

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RU 2 714 135 C1

Authors

Bespalov Aleksandr Yakovlevich

Prokopenko Lyubov Ivanovna

Gorchakova Tatyana Leonidovna

Kozlov Viktor Konstantinovich

Petrov Aleksandr Nikolaevich

Zajtseva Mariya Anatolevna

Melekhova Aleksandra Sergeevna

Belskaya Alisa Vladimirovna

Melnikova Margarita Viktorovna

Ivanov Maksim Borisovich

Dates

2020-02-12—Published

2019-11-22—Filed