7-[2-[4-(6-FLUORO-3-METHYL-1,2-BENZIOXAZOL-5-YL)-1-PIPERAZINYL]ETHYL]-2-(PROPYNYL)-7H-PYRAZOLO-[4, 3-e]-[1, 2, 4]-TRIAZOLO-[1, 5-c]PYRIMIDINE-5-AMINE Russian patent published in 2011 - IPC C07D487/14 A61K31/519 A61P25/14 A61P25/16

Abstract RU 2417997 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel compound - 7-[2-[4-(6-fluoro-3-methyl-1,2-benzioxazol-5-yl)-1-piperazinyl]ethyl]-2-(propynyl)-7H-pyrazolo-[4, 3-e]-[1, 2, 4]-triazolo-[1, 5-c]pyrimidine-5-amine or pharmaceutically acceptable salt thereof, having A_2a receptor selective antagonist properties, a pharmaceutical composition based on said compound and use thereof in preparing a medicinal agent for treating central nervous system diseases.

EFFECT: enhanced efficiency of composition and treatment method.

8 cl, 1 ex

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RU 2 417 997 C2

Authors

Bojl Krejg D.

Chakkalamannil Samjuehl'

Shakh Unmesh G.

Lakhovich Zhan Eh.

Dates

2011-05-10—Published

2006-09-21—Filed