MEDICIATION FOR PREVENTION AND TREATMENT OF ALCOHOL DEPENDENCE AND DEPENDENCE FROM MEDICATIONS Russian patent published in 2011 - IPC A61K31/454 A61K31/517 A61P25/30 A61P25/32 A61P25/34 A61P25/36

Abstract RU 2419433 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine and its application for prevention and treatment of abuse with psychoactive substances and dependence on psychoactive substances, which contains compound of formula (R)-2-{3-[1-(acenaphthene-1-yl)pyperidin-4-yl]-2,3-dihydro-2-oxo-benzimidazol-1-yl} -N-methyl acetamide or its pharmaceutically acceptable salt as active ingredient.

EFFECT: compound, which is agonist and has highly selective affinity to ORL-1 receptors, possesses effects of reduction of intensity of alcohol abstinence symptoms and suppression of surplus intake of alcohol and other psychoactive substances.

18 cl, 1 tbl, 8 dwg, 5 ex

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RU 2 419 433 C2

Authors

Tesima Kodzi

Chikkochioppo Roberto

Massi Mauritsio

Dates

2011-05-27—Published

2007-10-16—Filed