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(19)

(11)

2 451 017

(13)

(51)

IPC

C07D401/04(2006-01-01)

A61K31/454(2006-01-01)

A61P25/00(2006-01-01)

A61P25/20(2006-01-01)

A61P25/30(2006-01-01)

A61P25/32(2006-01-01)

(21) (22)

Application

2009136344/04, 2008-02-28

(24)

Start date

2008-02-28

(22)

Actual filing date

2008-02-28

(45)

Published

2012-05-20

(72)

Inventor

Nakano MasakazuMinoguti MasanoriKhanano TokusiOno Sin-ItiroKhoriuti KhidekiTesima Kodzi

(73)

Holder

Mitsubisi Tanabe Farma Korporejshn

BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF Russian patent published in 2012 - IPC C07D401/04 A61K31/454 A61P25/00 A61P25/20 A61P25/30 A61P25/32

Abstract RU 2451017 C2

FIELD: chemistry.

SUBSTANCE: described are novel compounds of general formula (I)

, where the value of each symbol is defined in the claim, which are ORL-1 receptor agonists.

EFFECT: improved bioavailability, based on improved metabolic stability, strong and high selectivity and can be used in medicine.

7 cl, 148 ex, 35 tbl

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RU 2 451 017 C2

Authors

Nakano Masakazu

Minoguti Masanori

Khanano Tokusi

Ono Sin-Itiro

Khoriuti Khideki

Tesima Kodzi

Dates

2012-05-20—Published

2008-02-28—Filed