PHARMACEUTICALLY ACTIVE COMPOUNDS, THEIR OBTAINING, COMPOSITIONS CONTAINING THEM AND THEIR APPLICATION Russian patent published in 2011 - IPC A61K33/24 A61K33/26 A61K33/08 A61P13/00 

Abstract RU 2420297 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: substance for application as a medication, including solid mixed compound of metals of formula (I): MII1-aMIIIaObAn-c·zH2O (I), where MII represents at least one bivalent metal, MIII represents Fe3+, An- represents at least one n-valent anion, z equals 2 or less, a = number of moles MIII /(number of moles MII + number of moles MIII), 2+a=2b+Σcn and Σcn<0.9a. Invention also relates to a method of obtaining said substance, which includes heating at temperature between 225°C to 550°C for 5 hours of compound, including structure of foliated double hydroxide. Invention also relates to application of said substance for obtaining a medication and pharmaceutical composition for binding phosphate and for prevention or treatment of hyperphosphatemia.

EFFECT: reducing the loss of bivalent metals in phosphate-binding substances.

33 cl, 6 tbl, 2 ex

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RU 2 420 297 C2

Authors

N'Juton Moris Sidni

Rouds Najdzhl Piter

Toft Aleksis Dzhon

Dates

2011-06-10Published

2006-02-09Filed