FIELD: medicine, pharmaceuticals.
SUBSTANCE: group of inventions relates to medicine, namely to gastroenterology and can be used for stimulation of locomotive function of gastrointestinal tract. Inventions include introduction of therapeutically effective amount of peptidyl analog of ghrelin, having a sequence H-Inp-D-Bal-D-Trp-Phe-Apc-NH2 (BIM-28131), its pharmaceutically acceptable salt or in pharmaceutical composition. For this purpose various methods characterising different ways of introducing said means for various conditions, accompanied by such abnormalities are offered.
EFFECT: inventions make it possible provide the most effective stimulation of locomotive activity of gastrointestinal tract in various types of abnormalities, due to selected ghrelin analog, which has by the factor of ten greater efficiency and duration of action in comparison with ghrelin.
30 cl, 5 dwg, 1 tbl, 8 ex
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|
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GRELIN ANALOGS | 2003 |
|
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|
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METHOD FOR THERAPEUTIC PEPTIDES SYNTHESIS | 2012 |
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|
RU2785889C1 |
Authors
Dates
2011-06-10—Published
2006-09-28—Filed