GHRELIN ANALOGUES Russian patent published in 2011 - IPC C07K14/575 A61K38/18 A61P5/06 

Abstract RU 2427587 C2

FIELD: medicine.

SUBSTANCE: invention relates to peptide analogues of formulae (I) and (II): (R2R3)- A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-A14-A15-A16-A17-A18-A19-A20-A21A22-A23-A24-A25-A26-A27-A28-R1 in which A1-A28 and R2-R3 are defined in the description for each of the formulae (I) and (II), pharmaceutically acceptable salts thereof and pharmaceutical compositions containing an effective amount of formula (I) compounds and which can be used in the method of suppressing growth hormone secretion and a method of screening a compound which is capable of binding with the GHS receptor.

EFFECT: high efficiency of using the composition.

31 cl, 5 tbl, 2 ex

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RU 2 427 587 C2

Authors

Dong Chzhen Ksin

Kaller Majkl Devitt

Shen Jilana

Komstok Dzhinn Mehri

Dates

2011-08-27Published

2006-09-27Filed