FIELD: chemistry.
SUBSTANCE: invention relates to peptidyl analogues of ghrelin having greater stability which are active with respect to the GHS receptor, having the formula given below: (R2)-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-A25-A26-A27-A28-Rl, where values of A1-A28, R1 and R2 are given in the description, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing an effective amount of said compound, as well as therapeutic and non-therapeutic applications thereof.
EFFECT: high stability.
22 cl, 3 tbl, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| GHRELIN ANALOGUES | 2006 |
|
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|
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| HUMAN GROWTH HORMONE SECRETION STIMULANTS | 2006 |
|
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| PEPTIDE DRUGS WITH HIGH EFFECTIVENESS AGAINST INSULIN RESISTANCE | 2012 |
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| THERAPEUTIC MEDICATION FOR ACCELERATED SKIN HEALING, WHICH CONTAINS AS ACTIVE INGREDIENT GRELIN AND ITS DERIVATIVES OR SUBSTANCE INFLUENCING GHS-RLa RECEPTOR | 2006 |
|
RU2420306C2 |
