COMPLEMENTARY PEPTIDE TO PRIMARY IMMUNOGENIC ACETYLCHOLINE RECEPTOR REGION, BASED THERAPEUTIC COMPOSITION, METHOD OF PRODUCING AND USING PEPTIDE Russian patent published in 2011 - IPC C07K7/04 A61K38/04 C07K1/00 C07K17/00 A61P25/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention discloses a complementary peptide having at least a sequence presented in the description and complementary to a primary immunogenic acetylcholine receptor region involved in myasthenia gravis, having at least the sequence SEQ ID NO:1 with tryptophan in position 8 and bearing at least one optionally substituted hydrocarbon group. There is disclosed therapeutic composition for treating myasthenia gravis based on the complementary peptide and applied for preparing a vaccine used in therapeutic and preventive treatment of myasthenia gravis in mammals. There are described methods of producing the complementary peptide and a drug and a method of treating myasthenia gravis in mammals with using the therapeutic composition.

EFFECT: invention provides the peptide showing an antigen behaviour and which can be used in treating MG in mammals, particularly dogs and humans.

22 cl, 11 dwg, 5 tbl, 3 ex