SURVIVIN PEPTIDE VACCINE Russian patent published in 2010 - IPC A61K39/00 

Abstract RU 2396088 C2

FIELD: medicine.

SUBSTANCE: invention refers to biotechnology. There is described a vaccine composition applicable for cancer treatment and containing: one or more versions of peptide fragments prepared of survivin protein where specified peptide fragment is chosen from the group consisting of: FTELTLGEF (SEQ ID NO: 16), LMLGEFLKL (SEQ ID NO: 5), EPDLAQCFY (SEQ ID NO: 9), APPAWQPFL (SEQ ID NO: 13) and RPPAWQPFL (SEQ ID NO: 14), and an adjuvant made as "water-in-oil" emulsion containing mineral oil and surface-active substance where said adjuvant contains to 14.5 vol. % of specified surface-active substance. There is offered a method for strong specific T-cell survivin response stimulation in a person, including introduction of the described vaccine, and also a method of cancer treatment or prevention in a person, including introduction of the described vaccine.

EFFECT: vaccine can be applied for preventive, relieving and/or medicinal treatment of eg oncological diseases.

14 cl, 3 dwg, 3 tbl, 2 ex

Similar patents RU2396088C2

Title Year Author Number
Bcl-2 PROTEINS, FRAGMENTS THEREOF, AND APPLICATION THEREOF IN PATIENTS WITH MALIGNANT TUMOUR 2004
  • Straten Ehjvind Per Tor
  • Andersen Mads Khal'D
RU2367468C2
VACCINATIVE TUMOR VACCINE COMPOSITION 2008
  • Sugiyama Kharuo
RU2682726C2
VACCINE COMPOSITION FOR MALIGNANT TUMOR 2013
  • Sugiyama Kharuo
RU2721574C2
PEPTIDE VACCINES FOR CANCER EXPRESSING MPHOSPH1 OR DEPDC1 POLYPEPTIDES 2007
  • Fudzioka Tomoaki
  • Nakamura Jusuke
  • Tsunoda Takuja
  • Osava Rjudzi
  • Sida Midori
RU2469044C2
URLC10-DERIVED PEPTIDE AND VACCINE CONTAINING SAME 2015
  • Tsunoda, Takuya
  • Osawa, Ryuji
  • Yamashita, Sachiko
  • Watanabe, Tomohisa
  • Hikichi, Tetsuro
RU2700881C2
KOC1-DERVIED PEPTIDE AND VACCINE INCLUDING SAME 2015
  • Tsunoda Takuya
  • Osawa Ryuji
  • Yamashita Sachiko
  • Watanabe Tomohisa
  • Hikichi Tetsuro
RU2699542C2
CDCA1-DERIVED PEPTIDE AND VACCINE CONTAINING SAME 2015
  • Tsunoda, Takuya
  • Osawa, Ryuji
  • Yamashita, Sachiko
  • Watanabe, Tomohisa
RU2699543C2
CDC45L PEPTIDES AND VACCINES CONTAINING SAME 2010
  • Nisimura Jasukharu
  • Tomita Jusuke
  • Nakamura Jusuke
  • Tsunoda Takuja
RU2562160C2
COMPOSITION FOR TREATING LUNG CANCER, FIRST NON-SMALL CELLS LUNG CANCER (NSCLC) 2008
  • Marijke Barner
  • Jokhen Probst
  • Tomas Lander
  • Ingmar Gerr
RU2526510C2
HELPER PEPTIDE FOR CANCER ANTIGEN 2010
  • Sugiyama Kharuo
RU2588442C2

RU 2 396 088 C2

Authors

Andersen Mads Khal'D

Dates

2010-08-10Published

2006-02-03Filed